RNAPro•SAL™
RNAPro•SAL™ was developed as an easy to use and cost effective tool for the split sample collection of rich sources of RNA (miRNA, mRNA) and proteins found in saliva. The kit provides two equivalent samples of saliva totaling 1.0 mL in 1–3 minutes, each ready for independent RNA or protein downstream analysis.
Key Features
Split Sample Collection
Provides two equivalent 0.5 mL saliva samples for simultaneous RNA and protein analysis from a single collection.
Sample Volume Adequacy Indicator
Built-in SVAI provides clear visual confirmation that an adequate quantity of sample has been collected.
Cell-Free Sample
Proprietary medium removes cells and unwanted components, delivering a clean, analysis-ready specimen.
Versatile Applications
Supports exosome isolation, liquid biopsy, cell-free DNA and RNA analysis, and proteomics workflows.
For Research Use Only (RUO)
RNAPro•SAL™ is intended for research use only in the United States and is not FDA-cleared for diagnostic use.
About RNAPro•SAL™
A split sample from a single collection
RNAPro•SAL™ is an easy-to-use, cost-effective tool for split sample collection of RNA (miRNA, mRNA) and proteins found in saliva. The kit provides two equivalent samples of saliva totaling 1.0 mL in 1–3 minutes, each ready for independent RNA or protein downstream analysis.
Cell-free and analysis-ready
A proprietary medium removes cells and unwanted components, so the specimen is clean and ready for analysis. A built-in sample volume adequacy indicator confirms visually that enough sample has been collected.
Applications
The kit supports exosome isolation, liquid biopsy, cell-free DNA and RNA analysis, and proteomics workflows.
Frequently Asked Questions
What does RNAPro•SAL collect?
A split sample of saliva for RNA (miRNA, mRNA) and protein analysis, as two equivalent 0.5 mL samples totaling 1.0 mL.
How long does collection take?
About 1–3 minutes.
Is the sample cell-free?
Yes. A proprietary medium removes cells and unwanted components.
What workflows does it support?
Exosome isolation, liquid biopsy, cell-free DNA and RNA analysis, and proteomics.
How do I know the sample is sufficient?
A built-in sample volume adequacy indicator gives a clear visual confirmation.
Resources
Publications
- 01 RNAPro•SAL: A Device for Rapid and Standardized Collection of Saliva RNA and Proteins (Wong D. 2015)
- 02 Human Salivary Protein Analysis Using RNAProSAL, PureSAL, and the Passive Drooling Method (Zohaib K. 2016)
- 03 A Simplified Method for the Isolation of Exosomes from Saliva (Laughlin M. 2015)
- 04 Comparison of RNAPro-SAL Saliva Collection Versus Centrifugation for Cell-Free DNA Isolation (Slowey P. 2015)
- 05 The Integrated Saliva Collection, Processing, Stabilization and Storage (iSCPSS) System (Wong D. 2014)
- 06 Guidelines for the standardization of pre-analytical variables for salivary biomarker studies in Alzheimer's disease research: An updated review and consensus of the Salivary Biomarkers for Dementia Research Working Group (Ng TKS. 2025)
- 07 Saliva Proteome, Metabolome and Microbiome Signatures for Detection of Alzheimer's Disease (François M. 2024)