5-Fluorouracil is a standard chemotherapy treatment for a number of malignancies, but a fraction of patients cannot metabolize 5-FU as quickly as anticipated, leading to an accumulation of high levels of the drug in the blood high levels of the drug: these subjects require a lower dosage or alternative chemotherapeutic agents in order to avoid life-threatening toxic side effects. The PGX-5FU StripAssay® provides a method to identify those individuals and ensure that the appropriate level of care is given to them. The PGX-5FU StripAssay® detects the DYPD *2A variant.
PGX-5FU StripAssay® Catalog 4-720
DPYD allele *2A (IVS14+1 G>A)